top of page

Characterization of Esophageal Cancers

& Metaplasia


Cover Site labo 01.jpg

The perception of taste allows one to assess whether ingested substances are nutritious or potentially hazardous, but this sense is frequently impaired in case of pathology or following chemotherapy. We recently identified taste buds clustered in the mouse esophagus and compared mechanisms regulating development of taste receptor cells in the tongue and esophagus at single cell resolution.

This study features on the cover of Science Advances

To learn more about the relationship between an embryonic transcriptomic program and columnar metaplasia in the esophagus, see our latest publication in Cell Stem Cell.

This work was supported by:

The Worldwide Cancer Research

The Télévie

The Fondation Contre le Cancer

Cover-HH 02.jpg
Illu chronotherapy new.jpg

In vitro models

Our recent study published in Biology suggests that response to therapy might be enhanced by optimizing the time of treatment (endogenous clock time). The full article can be found here.

bottom of page